Keywords: elderly urinary tract infections

        Urinary tract infection is a common disease of the elderly, second only to respiratory infections comes second in the infectious diseases of the elderly. Incidence of adult female urinary tract infection rate of 3% to 4.5%, more than 65 years of age increased from 15% to 20%. Few men before the age of 50 suffered from urinary tract infection, and 65-70 years of age may have 3% -4% of sick, elderly incidence of up to 20% or more after the age of 70. Regardless of any gender, is a chronic debilitating condition, or long-term hospitalization for bed, the incidence of urinary tract infections in the elderly can be as high as 25% -50%.

        Mechanism elderly susceptible to urinary tract infections are generally the following aspects:

        (1) The bacteria adhered to the surface of the urethral epithelial cells the ability to play an important role in the pathogenesis of urinary tract infection. The elderly urinary tract epithelial cells increased sensitivity to bacterial adhesion.

        (2) the elderly urinary tract obstruction and poor urine flow factors significantly increase, such as benign prostatic hyperplasia or bladder neck obstruction and urinary tract stones, tumors, etc., there are incomplete or complete obstruction of urinary tract, the bacteria easy to survival and reproduction.

        (3) the humoral and cellular immune function of the elderly decreased significantly reduced its ability to respond to infection and other stress factors. Meanwhile, in relative ischemia due to atherosclerosis, pelvic muscle relaxation, the the elderly kidney and bladder mucosa habitual constipation can be further exacerbated the local mucosal’s blood circulation poor, reduced secretion of prostate fluid, so that the local resistance loss. In addition, the elderly kidney degenerative changes, especially the distal convoluted tubule and collecting duct diverticulum or cyst formation, is also one of the reasons for the decline of the urinary tract mucosal defense mechanism.

        (4) decreased elderly physiological thirst, drinking water and lower tubular urine concentration dilution function change factor is susceptible to urinary tract infections.

        The same time, the elderly are often associated with high blood pressure, diabetes and other systemic diseases, malnutrition and prolonged bed rest, analgesics, non-steroidal anti-inflammatory drugs such as abuse because of illness, and therefore prone to urinary tract infections.