Keywords: bile reflux gastritis after gastrectomy
Gastrectomy bile reflux gastritis (postgastrectomy bilereflux gastrieis) gastrectomy, pyloric dysfunction resulting bile reflux gastritis. It is also known as reflux liquid is alkaline, alkaline reflux gastritis after gastrectomy.
Long-term follow-up study showed that the gastrectomy chronic superficial or chronic atrophic gastritis incidence of up to 95%, most likely related to bile reflux. In Pythagoras’ I, the Pythagorean II after high incidence, while vagotomy surgery had the lowest.
Etiology and pathology of bile reflux gastritis after gastrectomy
Stomach surgical resection of pyloric or vagus nerve axotomy innervation of the pyloric lost the opportunity to significantly increased duodenal contents reflux into the stomach. Wherein cholic acid soluble lipoproteins and destruction of mucosal barrier function of the H + into the gastric cavity, and H + into the gastric mucosa from the stomach cavity. H + into the gastric mucosa but also stimulate mast cells to release histamine. The latter in turn stimulates the secretion of gastric acid and pepsin, thereby aggravating the injury of the gastric mucosa and produce inflammation, erosions and ulcers. Duodenal juice, pancreatic juice and bile acid damage to the gastric mucosa more synergy. In addition, stomach surgery, especially the Pythagorean II after surgery, the gastric mucosal barrier to strengthen the role of H + antiporter dispersion effect of gastrin secretion resistant to reduce, weaken the barrier function of the gastric mucosa, but also the incidence of reflux gastritis factors one.