Keywords: coronary heart disease
The risk of coronary artery disease, about 99% are caused by coronary atherosclerosis. So, coronary heart disease actually refers to coronary atherosclerotic heart disease, referred to as coronary heart disease.
When coronary atherosclerosis development to a certain extent, a result of a severe stenosis of the lumen of the coronary arteries, blocking can cause myocardial ischemia and hypoxia, which occurred in a series of symptoms (such as chest tightness, angina), or even myocardial infarction and life-threatening. This disease is coronary atherosclerotic heart disease. Its essence is myocardial ischemia. It is also known as ischemic heart disease.
Boat of the normal artery wall is divided into three layers: intima, media and adventitia. Intimal layer of smooth flat epithelial cells, extremely slim, smooth, to ensure the free flow of blood in the arteries; middle by smooth muscle, systolic and diastolic function: adventitia relatively loose layer of protection organizations. Normal arterial wall is quite soft and flexible, with the section move diastolic and systolic heart. Artery for various reasons, loss of elasticity and harden, medicine, collectively referred to as dynamic knee hardening. Arteriosclerosis, according to its causes, consequences and pathological different, can be largely divided into three types of: ① small power pulse hard. Thickening and hardening of major hair the middle arterial calcification in hypertensive patients. Medium-sized arteries occur in the limbs, a glue does not cause stenosis, does not produce symptoms. ② atherosclerosis. Often occurs in large arteries, the blood vessels of the important parts of the aorta, coronary, cerebral artery. Atherosclerosis is a lipid metabolism disorders, especially cholesterol metabolism drop obstacle is closely related to the disease. Early lesions, blood cholesterol and other lipids and complex carbohydrates in the arterial intima settle down, which in turn cause intimal fibrous tissue hyperplasia, endometrial gradually uplift, thickening, formation of the the sallow plaque naked eye can see; after plaque expanding soften, the collapse of the center in part because of inadequate nutrition, the visible yellow “atherosclerosis" substances; then after middle artery lipid settle down, and the middle of the elastic fibers and the almost smooth muscle fiber breakage intimal gradually under the fibrous tissue proliferation, as well as calcium precipitated a result, the artery walls become brittle, hardened, luminal narrowing, this lesion called atherosclerosis. It is leading to myocardial ischemia, coronary heart disease is the main reason.